Azithromycin fails to ameliorate treatment-resistant cough

May 26, 2016

Azithromycin does not appear to be an effective agent for those with treatment-resistant cough, but may be useful in treating those with comorbid asthma, according to the results of a study published in Chest.

David Hodgson, Ph.D., from the Nottingham Respiratory Research Unit at the University of Nottingham (England), and colleagues conducted an 8-week randomized, double-blind, placebo-controlled parallel group trial with follow-up visits at 4, 8, and 12 weeks to determine whether treatment with low-dose azithromycin would affect the Leicester Cough Questionnaire (LCQ) score, cough severity on a visual analog scale, and fraction of exhaled nitric oxide (FENO) in patients with treatment-resistant chronic cough. (Chest. 2016 Apr;149[4]:1052-60. doi: 10.1016/j.chest.2015.12.036).

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