Adult Chronic Sinusitis and Its Complications

Infectious agents (especially upper respiratory viral agents)
Exposure to external irritants

Air pollution
Smoking
Cocaine abuse

Anatomical abnormalities

Septal deviation
Turbinate hypertrophy
Nasal polyposis
Prolonged use of nasogastric tube

History of hyperactivity

Allergic rhinitis
Asthma

Deficiencies in immune response

IgG or IgA subclass deficiencies
Common variable immunodeficiency
AIDS

Certain comorbid conditions

Pregnancy
Poorly controlled diabetes mellitus
Cystic fibrosis
Ciliary dyskinesia