Ventilator - Induced Lung Injury

By Neil R. MacIntyre, MD, FCCP

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Introduction

• Figure 1

Mechanisms & Pathogenesis of VILI

• Alveolar Overdistention & the Development of Lung Injury
• Figure 2
• Mechanisms of Lung Injury & the Development of Systemic Inflammation
• The Role of Cyclical Alveolar Collapse

Management Strategies To Reduce VILI

• Determining Underrecruitment & Overdistention in the Lung
• Conventional Mechanical Ventilation Strategies for Providing Lung Protection
• Table 1
• Future Directions

Conclusions
Poststudy Questions
References