Ventilator - Induced Lung Injury

By Neil R. MacIntyre, MD, FCCP

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Management Strategies To Reduce VILI

To minimize VILI, mechanical ventilation goals should be twofold. The first goal should be to provide enough PEEP to recruit the "recruitable" alveoli while at the same time not applying so much PEEP that healthier regions are unnecessarily overdistended.^53-56 The second goal should be to avoid a PEEP-tidal volume (VT) combination that unnecessarily overdistends lung regions at end inspiration.^55,56 These goals embody the concept of a lung-protective mechanical ventilatory strategy.

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