Mesothelioma Update

By Mark Block, MD; and Alice M. Boylan, MD

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Radiation Therapy

Although in vitro studies suggest that mesothelioma is more sensitive to radiation than non-small cell lung cancer, the clinical experience reported by radiation oncologists suggests that it is an especially radioresistant tumor. In addition, radiation of the involved chest is limited by the presence of radiosensitive organs. As a consequence, its use appears limited to adjunctive therapy for patients who have undergone EPP, and to palliative treatment of painful chest wall lesions.

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