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Pulmonary Vascular Disease NetWork

Curriculum - High Altitude Pulmonary Edema

Gabry AL, Ledoux X, Mozziconacci M, Martin C. High-altitude pulmonary edema at moderate altitude (< 2,400 m; 7,870 feet): a series of 52 patients. Chest 2003. Swenson ER, Maggiorini M, Mongovin S, Gibbs JS, Greve I, Mairbaurl H, Bartsch P. Pathogenesis of high-altitude pulmonary edema: inflammation is not an etiologic factor. Jama 2002. PubMed Abstracts

Richalet JP, Gratadour P, Robach P, Pham I, Dechaux M, Joncquiert-Latarjet A, Mollard P, Brugniaux J, Cornolo J. Sildenafil inhibits altitude-induced hypoxemia and pulmonary hypertension. Am J Respir Crit Care Med 2005. PubMed Abstracts

Alleman Y, Hutter D, Lipp E, Sartori C, Duplain H, Egli M, Cook S, Scherrer U, Seiler C.  Patent foramen ovale and high-altitude pulmonary edema. JAMA 2006; 296(24):2954-8 PubMed Abstracts

Ashan A, Mohd G, Norboo T, Baig MA, Pash MA.  Heterozygotes of NOS3 polymorphisms contribute to reduced nitrogen oxides in high-altitude pulmonary edema. Chest 2006; 130(5):1511-9 PubMed Abstracts

West JB.  Adventures in high-altitude physiology. Adv Exp Med Biol 2006; 588:7-16. PubMed Abstracts

Maggiorini M, Brunner-La Rocca HP, Peth S, Fischler M, Bohm T, Bernheim A, Kiencke S, Bloch KE, Dehnert C, Naeije R, Lehmann T, Bartsch P, Mairbaurl H.  Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial. Ann Intern Med 2006; 145(7):497-506 PubMed Abstracts

Rupert JL, Koehle MS.  Evidence for a genetic basis for altitude-related illness. High Alt Med Biol 2006; 7(2):150-67 PubMed Abstracts

Bartsch P, Mairbaurl H, Maggiorini M, Swenson ER.  Physiological aspects of high-altitude pulmonary edema. J Appl Physiol 2005; 98(3):1101-10 PubMed Abstracts