CHESTGuidelines & Topic CollectionsEarly-Stage NSCLC: Advances in Diagnosis, Tissue Acquisition, and Treatment

Early-Stage NSCLC: Advances in Diagnosis, Tissue Acquisition, and Treatment

Recorded: July 24, 2025

This webinar explores the evolving landscape of diagnosis and treatment for stage I and II non-small cell lung cancer (NSCLC). Viewers will gain critical insights into current best practices in tissue acquisition, including the role of high-quality biopsies and biomarker testing strategies. Expert faculty walk through the latest diagnostic algorithms, highlight key differences in management based on epidermal growth factor receptor and anaplastic lymphoma kinase mutation status, and examine treatment pathways, including surgery, perioperative systemic therapy (including targeted therapy and immunotherapy), and stereotactic body radiation therapy for patients who are inoperable.

The session also addresses interdisciplinary coordination in early-stage lung cancer care and equips clinicians with up-to-date guidance for integrating molecular profiling into therapeutic decision-making.

This non-CME education is brought to you by CHEST and sponsored by AstraZeneca.


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Moderator

Gerard A. Silvestri, MD, MS, Master FCCP

Hillenbrand Distinguished University Professor
Senior Vice-Chair of Faculty Development
Department of Medicine
Medical University of South Carolina
Charleston, SC


Panelist

Charu Aggarwal, MD, MPH, FASCO

Leslye M. Heisler Professor of Lung Cancer Excellence
Section Chief, Thoracic and Head & Neck Cancer
Associate Director, Penn Center for Cancer Care Innovation (PC3I)


Panelist

Anne V. Gonzalez, MD, FCCP

Centre for Outcomes Research and Evaluation
Associate Professor, Department of Medicine
Faculty of Medicine and Health Sciences, McGill University
Department of Medicine, Division of Respiratory Medicine
McGill University Health Centre


Panelist

Jeffrey Velotta, MD, FACS

Clinical Professor
Department of Clinical Science
Kaiser Permanente Bernard J. Tyson School of Medicine
Clinical Assistant Professor
Department of Surgery
University of California, San Francisco School of Medicine


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