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Pulmonary Vascular Disease

Pulmonary Vascular Disease

CHEST’s pulmonary vascular disease resources help guide clinicians in providing the highest-quality care for patients with these conditions. Access original research from the journal CHEST®, clinical practice guidelines, CHEST Physician articles, podcasts, video lectures, and educational courses and events.

CHEST Journal Highlights

Sex Differences in Portopulmonary Hypertension

By: Hilary M. DuBrock, MD; Rodrigo Cartin-Ceba, MD; Richard N. Channick, MD; Steven M. Kawut, MD; and Michael J. Krowka, MD
January 2021 Issue
Portopulmonary hypertension (POPH) can lead to right-sided heart failure and death. In this study, the authors sought to characterize sex differences in clinical characteristics, pulmonary hemodynamics, treatment response, and survival in patients with POPH.

BMI Is Causally Associated With Pulmonary Artery Pressure But Not Hemodynamic Evidence of Pulmonary Vascular Remodeling

By: Timothy E. Thayer, MD; Rebecca T. Levinson, PhD; Shi Huang, PhD; et al
January 2021 Issue
There is an unclear relationship of obesity to the pathogenesis and severity of pulmonary arterial hypertension and pulmonary venous hypertension. Is BMI casually associated with pulmonary artery pressure and/or markers of pulmonary vascular remodeling?

Development and Validation of an Abridged Version of the REVEAL 2.0 Risk Score Calculator, REVEAL Lite 2, for Use in Patients With Pulmonary Arterial Hypertension

By: Raymond L. Benza, MD; Manreet K. Kanwar, MD; Amresh Raina, MD; et al
January 2021 Issue
Risk calculators that assess fewer variables without compromising validity may expedite risk assessment in the routine clinic setting. The authors examine whether a simplified version of the REVEAL 2.0 risk assessment calculator for patients with pulmonary arterial hypertension can be developed and validated.


Mixed Venous Oxygen Saturation in Patients With PAH

Is mixed venous oxygen saturation (SvO2) a better measurement than cardiac index (CI) to assess prognosis in patients with pulmonary arterial hypertension?

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This retrospective study assessed correlation between SvO2 and CI measured by thermodilution and determined concordance in risk group allocation.

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Survival was impacted by SvO2 but not by CI risk group allocation.


Read the related article: Mixed Venous Oxygen Saturation Is a Better Prognosticator Than Cardiac Index in Pulmonary Arterial Hypertension »

CHEST Journal | Access the journal CHEST's full collection of pulmonary vascular disease research.  Read the journal »

CHEST 2020 Recorded Sessions


Pulmonary Vascular Disease Sessions On Demand

Couldn't attend CHEST Annual Meeting 2020? Gain access to all of the recorded sessions from the meeting with this unique collection that includes the latest presentations from top clinicians and researchers in chest medicine, including diagnostics and management of pulmonary hypertension, a case-based discussion of acute pulmonary embolism, the crashing PAH patient, and more.

Purchase access now »

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CHEST Pulse Podcast

Virchow’s Triad and the Perfect Storm: VTE in Patients With COVID-19

Ryan Maves, MD, FCCP, interviews authors of the “Prevention, Diagnosis, and Treatment of Venous Thromboembolism in Patients With Coronavirus Disease 2019: CHEST Guideline and Expert Panel Report.”

Moderator: Ryan Maves, MD, FCCP
Panelists: Lisa Baumann Kreuziger, MD; David Jimenez, MD, PhD; Lisa K. Moores, MD, FCCP; and Tobias Tritschler, MD

Also available:

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Patient Information

The CHEST Foundation creates trusted patient education resources that empower patients to engage in better managing their health.

Navigating PAH: Patient Education Guide
PAH Infographic
PAH Myths Busted

e-Learning Courses

Gain access to pulmonary vascular disease e-learning materials with a subscription to CHEST’s e-Learning Library.


When Is It Not PAH?

This podcast emphasizes ways to identify non-PAH patients with chronic heart failure, normal wedge pressures, and hypoxic lung disease.

CME Available: .5 AMA PRA Category 1 Credit


InPHOCUS Pulmonary Hypertension Self-Study Module

This module focuses on effective pulmonary hypertension diagnosis, personalized assessment, and treatment with an emphasis on PAH and CTEPH.

CME Available: 2.5 AMA PRA Category 1 Credits


Sorting Out HFpEF and Pulmonary Hypertension

Learn how to apply clinical, echocardiographic, and hemodynamic criteria to diagnose and treat patients with heart failure with preserved ejection fraction (HFpEF).

CME Available: .5 AMA PRA Category 1 Credit

CHEST E-LEARNING LIBRARY Customize a learning plan specific to your needs. Subscribe today »

CHEST SEEK™ Education

Written and peer reviewed by renowned experts in the pulmonary, critical care, and sleep medicine fields, the online CHEST SEEK Library and print publications include case-based questions and detailed rationales to stimulate and challenge your clinical thought processes; help you prepare for certification or recertification exams; and allow you to obtain CME credit, MOC points, and CE hours.

Take the CHEST SEEK Challenge and answer a sample question.

A 65-year-old woman has a fracture of the left femoral neck after tripping and falling at home. Her medical history is notable for breast cancer 5 years ago, which was treated with lumpectomy and chemotherapy. Her current medications are anastrozole, omeprazole, and lisinopril. She is a former smoker and has no history of COPD. Creatinine clearance rate is estimated at >60 mL/min.

She is admitted to the medicine service, and surgical repair is planned in approximately 4 h. In addition to intermittent pneumatic compression devices applied to the lower extremities, which pharmacologic VTE prophylaxis should be administered at this time?

A. Enoxaparin
B. Aspirin
C. Unfractured heparin
D. No pharmacologic prophylaxis

Submit your email address for the correct answer

CHEST SEEK LIBRARY | Access hundreds of pulmonary, critical care, and sleep medicine questions.  Purchase now »

Latest News From CHEST Physician

Evaluating PH AVR visual abstract

COVID-19 & Pulmonary Vasculature—An Intriguing Relationship

By Humna Abid Memon, MD
Fellow-in-Training Member, Pulmonary Vascular Disease NetWork Steering Committee

Dr. Memon highlights recent literature on the complex and multifaceted relationship between COVID-19 and pulmonary vasculature, which may prove to be insightful for discovering potential therapeutic targets in COVID-19.

From the NetWorks

Jean Elwing, MD, FCCP

Jean Elwing, MD, FCCP
Chair, Pulmonary Vascular Disease NetWork

Get the latest updates from CHEST’s Pulmonary Vascular Disease NetWork.


Pulmonary Vascular Lecture

PAH Risk Assessment: Overview and Review of PVD NetWork Survey

Vijay Balasubramanian, MD, FCCP, Medical Director of Pulmonary Hypertension-Community Regional Medical Center at UCSF Fresno, and Jean Elwing, MD, FCCP, Director of the Pulmonary Hypertension Program at the University of Cincinnati Health in Ohio, discuss the results of the Pulmonary Vascular Disease NetWork’s survey on how clinicians have implemented risk assessment tools to evaluate and monitor patients with pulmonary arterial hypertension.


Pulmonary Board Review On Demand

Earn up to 52 CME credits with access to the recorded sessions from Board Review 2020. Learn from comprehensive, exam-focused review sessions covering targeted content in pulmonary medicine, including pulmonary arterial hypertension, thromboembolic disease, and vasculitis and alveolar hemorrhage.


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Join the Community

If you’re not already a CHEST member, become one today for access to additional resources, discounts on educational activities, and networking opportunities. Join now »