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Pulmonary Vascular Disease

Pulmonary Vascular Disease

CHEST’s pulmonary vascular disease resources help guide clinicians in providing the highest-quality care for patients with these conditions. Access original research from the journal CHEST®, clinical practice guidelines, CHEST Physician articles, podcasts, video lectures, and educational courses and events.

CHEST Journal Highlights

The Value of Hemodynamic Measurements or Cardiac MRI in the Follow-up of Patients With Idiopathic Pulmonary Arterial Hypertension

By: Cathelijne Emma van der Bruggen, MD; Martin Louis Handoko, MD, PhD; Harm Jan Bogaard, MD, PhD; et al
April 2021 Issue
Treatment of patients with pulmonary arterial hypertension (PAH) is conventionally based on functional plus invasive measurements obtained during right heart catheterization. But how does the predictive value of noninvasive parameters compare with that of invasive hemodynamic measurements 1 year after the diagnosis of idiopathic PAH?

Renin-Angiotensin-Aldosterone System Inhibitor Use and Mortality in Pulmonary Hypertension

By: Tim Lahm, MD; Edward Hess, MS; Anna E. Barón, PhD; et al
April 2021 Issue
In this study, the authors investigated whether renin-angiotensin-aldosterone system inhibitor use is associated with lower mortality in a large cohort of patients with hemodynamically confirmed pulmonary hypertension.

Read the related editorial: Identifying New Targets for Treatment of Pulmonary Hypertension »

A Case Report of Portopulmonary Hypertension Precipitated by Transjugular Intrahepatic Portosystemic Shunt

By: Jasmine H. Tatah, MHS; E. Kenneth Weir, MD; Kurt W. Prins, MD, PhD; and Thenappan Thenappan, MD
April 2021 Issue
The authors describe the case of a 59-year-old woman who was referred for pulmonary hypertension evaluation because a dobutamine stress echocardiogram performed as part of liver transplantation evaluation showed right ventricular (RV) dilation and elevated RV systolic pressure.


Mixed Venous Oxygen Saturation in Patients With PAH

Is mixed venous oxygen saturation (SvO2) a better measurement than cardiac index (CI) to assess prognosis in patients with pulmonary arterial hypertension?

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This retrospective study assessed correlation between SvO2 and CI measured by thermodilution and determined concordance in risk group allocation.

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Survival was impacted by SvO2 but not by CI risk group allocation.


Read the related article: Mixed Venous Oxygen Saturation Is a Better Prognosticator Than Cardiac Index in Pulmonary Arterial Hypertension »

CHEST Journal | Access the journal CHEST's full collection of pulmonary vascular disease research.  Read the journal »

CHEST Journal Podcast

Incidence of VTE and Bleeding Among Hospitalized Patients With COVID-19

Listen to a discussion on the incidence of venous thromboembolism and bleeding among hospitalized patients with COVID-19.

Moderator: Dominique Pepper, MD
Panelists: David Jimenez, MD, PhD, and Lisa K. Moores, MD

Read the related article: Incidence of VTE and Bleeding Among Hospitalized Patients With Coronavirus Disease 2019 »

Also available:

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Patient Information

The CHEST Foundation creates trusted patient education resources that empower patients to engage in better managing their health.

Navigating PAH: Patient Education Guide
PAH Infographic
PAH Myths Busted

CHEST Player Hub

PAH Jeopardy!

Immerse yourself in a timeless, mobile game of Jeopardy! Test your pulmonary arterial hypertension knowledge by answering the questions on the gameboard surrounding diagnosis and treatment of patients.

Start playing now »

Supporter information can be found in the Player Hub.

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e-Learning Courses

Stay on the cutting edge of patient care and earn CME credit with learning opportunities available exclusively through CHEST.


Comprehensive Review in Pulmonary Hypertension

This on demand course provides an in-depth review of appropriate diagnosis and current treatment guidelines.

CME/MOC Available: 4.0 CME credits and MOC points


Pulmonary Hypertension Spotlight

Learn about guideline and treatment algorithm updates, the role of risk stratification in treatment selection, diagnostic and therapeutic challenges, treatment of critically ill patients, and treatment of patients with pulmonary hypertension.

CME/MOC Available: 5.0 CME credits and MOC points


Pulmonary Update and Literature Review

Leading experts review the published literature and provide updates on treatment options in eight important pulmonary topics.

CME/MOC Available: 8.0 CME credits and MOC points

CHEST E-LEARNING LIBRARY Customize a learning plan specific to your needs. Subscribe today »

CHEST SEEK™ Education

Written and peer reviewed by renowned experts in the pulmonary, critical care, and sleep medicine fields, the online CHEST SEEK Library and print publications include case-based questions and detailed rationales to stimulate and challenge your clinical thought processes; help you prepare for certification or recertification exams; and allow you to obtain CME credit, MOC points, and CE hours.

Take the CHEST SEEK Challenge and answer a sample question.

A 65-year-old woman has a fracture of the left femoral neck after tripping and falling at home. Her medical history is notable for breast cancer 5 years ago, which was treated with lumpectomy and chemotherapy. Her current medications are anastrozole, omeprazole, and lisinopril. She is a former smoker and has no history of COPD. Creatinine clearance rate is estimated at >60 mL/min.

She is admitted to the medicine service, and surgical repair is planned in approximately 4 h. In addition to intermittent pneumatic compression devices applied to the lower extremities, which pharmacologic VTE prophylaxis should be administered at this time?

A. Enoxaparin
B. Aspirin
C. Unfractured heparin
D. No pharmacologic prophylaxis

Submit your email address for the correct answer

CHEST SEEK LIBRARY | Access hundreds of pulmonary, critical care, and sleep medicine questions.  Purchase now »

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CHEST 2020 Recorded Sessions


Pulmonary Vascular Disease Sessions On Demand

Couldn't attend CHEST Annual Meeting 2020? Gain access to all of the recorded sessions from the meeting with this unique collection that includes the latest presentations from top clinicians and researchers in chest medicine, including diagnostics and management of pulmonary hypertension, a case-based discussion of acute pulmonary embolism, the crashing PAH patient, and more.

Purchase access now »

Watch a preview of what you can expect from the CHEST 2020 Recorded Sessions.

Join the Community

If you’re not already a CHEST member, become one today for access to additional resources, discounts on educational activities, and networking opportunities. Join now »