In brief: what’s new and notable in sepsis

Explore research into sepsis-related mortalities, insights into escalating vasopressor and corticosteroid therapy in patients with septic shock, and updates from the Sepsis/Shock Section of CHEST's Critical Care Network. Review infographics on conditions that mimic sepsis, molecular methods that may be able to rapidly identify pathogens and drug resistance, and tips for treating patients with pneumonia and sepsis.


Sepsis research, news, and notes

Additional research in sepsis

Review other important research in sepsis selected by members of the Sepsis Resources Steering Committee, including studies exploring performance improvement programs for sepsis and sepsis early warning systems.


News, notes, and opinions in sepsis medicine


Now we have MERCY
MERCY adds to the existing body of evidence suggesting that prolonged and intermittent infusion strategies for meropenem are at least equivalent in efficacy.

We need more efforts to prevent sepsis readmissions
Though sepsis is not a direct readmission measure, it could be one in the future.

Fluid Resuscitation – Back to BaSICS
The age-old debate regarding the appropriate timing, volume, and type of fluid resuscitation for patients in septic shock rages on – or does it?


Sepsis-induced cardiomyopathy: Is it time to establish a standard of care?
Sepsis-induced cardiomyopathy (SICM) complicates greater than 10% of sepsis and septic shock cases. But no universal definition of SICM exists, making diagnosis and evaluation of novel therapeutic options difficult.


SEP-1 protocol to manage severe sepsis and septic shock
Read the letter CHEST and the Society of Critical Care Medicine issued to the National Quality Forum in support of the continued use of the SEP-1 quality measure, including research addressing the concerns of organizations advocating against renewing the measure.


The mission of the Sepsis Resources Steering Committee—made up of leaders from the CHEST membership with a clinical expertise in sepsis management—is to curate a collection of resources designed to help guide and inform the care clinicians deliver to patients with sepsis. This committee aims to provide clinicians with the latest guidance and research to help enhance sepsis prevention practices and improve patient outcomes.

Steven Q. Simpson, MD, FCCP, Chair

Steven Q. Simpson,
MD, FCCP, Chair

CHEST President, 2020-2021

Christopher Carroll, MD, FCCP

Christopher Carroll,

Board of Regents, Regent-at-Large, and Critical Care Network, Chair

Angel Coz Yataco, MD, FCCP

Angel Coz Yataco,

Council of Networks, Chair

Alice Gallo De Moraes, MD, FCCP

Alice Gallo De Moraes,

Mechanical Ventilation and Airways Management Section, Member

Ryan Maves, MD, FCCP

Ryan Maves,

Disaster Response and Global Health Section, Chair

H. Bryant Nguyen, MD, MS

H. Bryant Nguyen,

Sepsis/Shock Section, Chair

Katie Pendleton, MD, FCCP

Katie Pendleton,

Sepsis/Shock Section, Vice-Chair

Marcos Restrepo, MD, PhD, FCCP

Marcos Restrepo,

Chest Infections and Disaster Response Network, Chair

These resources were supported by Grant/Cooperative Agreement Number 5 NU50CK000604-02-00 from the Department of Health and Human Services, Centers for Disease Control and Prevention. The contents are solely the responsibility of the authors and do not necessarily represent the official views of the Department of Health and Human Services, Centers for Disease Control and Prevention.