Guideline in Focus
Management of Adult Bronchiectasis

Without appropriate management, patients with bronchiectasis can experience reduced quality of life and declining lung function. This guideline provides 13 evidence-based recommendations addressing duration and route of antibiotic therapy, long-term suppressive antibiotic and anti-inflammatory therapies, airway clearance strategies, and more.

PUBLISHED JULY 21, 2026

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Key Recommendations

For adults with frequent exacerbations of bronchiectasis, we suggest long-term inhaled antibiotic therapy.

For adults with frequent exacerbations of bronchiectasis, we suggest long-term macrolide therapy.

For adults with frequent exacerbations of bronchiectasis, we suggest long-term brensocatib therapy.


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High-resolution CT scan
Needed to confirm
bronchiectasis diagnosis
3+
months

Long-term inhaled
antibiotic therapy course
2+
per year

Defined as
frequent exacerbations

Implement this guideline into practice

Our guidelines are aimed at helping you respond to today’s clinical challenges and improve patient health outcomes. Our panel of experts has developed multimedia content to facilitate adoption of this guideline into your day-to-day practice.


PRESS RELEASE

CHEST Releases Guideline on Managing Adult Bronchiectasis
In a release issued to the media, lead author Rachel Thomson, MBBS, FCCP, speaks to the importance of this guideline in practice.

2 MINUTE READ

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