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This free CHEST e-Learning course was created based on the materials from the CHEST Annual Meeting 2018 Severe Asthma Fellows Course. This course contains highlighted content of a full-day course with relevant presentations from respected leaders in severe asthma and is targeted toward physicians-in-training who specialize in this area.

Includes:

Asthma Immunology

Reynold Panettieri, MD
Vice Chancellor of Translational Medicine and Science
Rutgers University
New Brunswick, New Jersey

Overview of inflammatory cascade, understand classic allergic, eosinophilic, and independent pathways and how they overlap (IgE, ILD4, IL5, IL14). General framework for how the drugs will actually work.

Severe Asthma Definition/Intro to Phenotyping and Biomarkers 

Monica Kraft, MD,  FCCP 
Robert and Irene Flinn Professor of Medicine
Chair, Department of Medicine
Deputy Director, Asthma and Airway Diseases Research Center
University of Arizona Health Sciences Center
Tucson, Arizona

Diving into what we mean by “severe asthma” (ATS/ERS definitions). Use immunology basis of different types of asthma (allergen sensitization to type2/non-type 2/Th17,etc).

Severe Asthma Mimickers

Jay Peters, MD, FCCP
Chief, Pulmonary and Critical Care Medicine
University of Texas Health Science Center
San Antonio, Texas
Covers VCD, COPD/asthma overlap, severe reflux, and sinus disease.

Practical Approach to Severe Asthma Therapies: Putting It All Together
Monica Kraft, MD, FCCP  
Robert and Irene Flinn Professor of Medicine
Chair, Department of Medicine
Deputy Director, Asthma and Airway Diseases Research Center
University of Arizona Health Sciences Center
Tucson, Arizona
Focuses on a case-based approach.

Biologics

Param Nair, MD 
Frederick E. HargreaveTeva Innovation Chair in Airway Diseases 
Professor of Medicine, McMaster University
Adjunct Professor of Medicine, McGill University 
Staff Respirologist, St. Joseph’s Healthcare 
Firestone Institute for Respiratory Health
Hamilton, Ontario, Canada

Non-Eosinophilic Advanced Therapies

Gerry Cox, MD  
Firestone Institute for Respiratory Health–McMaster University
Hamilton, Ontario, Canada

Covers bronchial thermoplasty (who to consider this for, mostly IP procedure), macrolides, and other experimental drugs.